3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate

3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate - Names and Identifiers

Name	3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate
Synonyms	Medroxyprogesterone Acetate Impurity 17 17α-Acetoxy-3-ethoxypregna-3,5-dien-20-one 17-Acetyloxy-3-ethoxypregna-3,5-dien-20-one 3-Ethoxypregna-3,5-dien-17-ol-20-one-17-acetate Pregna-3,5-dien-20-one, 17-(acetyloxy)-3-ethoxy- 3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate
CAS	16319-93-0
EINECS	240-396-4

3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate - Physico-chemical Properties

Molecular Formula	C25H36O4
Molar Mass	400.55
Storage Condition	Room Temprature
Physical and Chemical Properties	Chemical properties crystallization.
Use	Use an intermediate of megestrol.

3-ethoxy-17-hydroxypregna-3,5-dien-20-one 17-acetate - Production method

16 α,17 α-epoxyprogesterone -4-ene -3,20-dione (I. e. epoxyprogesterone) can be added (epoxy group and hydrogen bromide) to form 16-Bromine, 17 α-hydroxyl), catalytic hydrogenation (bromine removal), (3-ketone, 4-position double bond conversion to 3-position hydroxyl, 3-position and 5-position double bond, then 3-hydroxyl group, 17 α-hydroxyl group) acetylation, hydrolysis (removal of 3-acetyl group), (3-hydroxyl group) etherification to prepare the product.

Last Update：2024-04-10 22:29:15